MycoBiomDB – Record Details (MyCo_3771)

Biomarker Record Details

Database ID: MyCo_3771
DB IDMyCo_3771
TitleEarlier diagnosis of invasive fusariosis with Aspergillus serum galactomannan testing
Year2014
PMID24489964
Fungal Diseases involvedInvasive fusariosis
Associated Medical ConditionNone
GenusFusarium
Speciesoxysporum
OrganismFusarium oxysporum
Ethical StatementThe study was approved by the institutions’ ethical committees, and a waiver of the need for written informed consent was granted, because of the observa- tional nature of the study: Comite de Etica em Pesquisa do Hospital Universita ´rio Clementino Fraga Filho and Comite de Etica em Pesquisa da Unifesp/EPM.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationBrazil
CohortBetween 2008 and 2012, 25 cases of invasive fusariosis were diagnosed in the three institutions. Seven cases were excluded; four because no GMI tests were performed in the period, and three because the closest GMI test was .2 days from the date of the first clinical manifestation of invasive fusariosis. The main characteristics of the remaining 18 cases.
Cohort No.18
Age Group10–69
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodGM Assay
ELISA kitsNone
Assay DataNone
Validation Techniques usedGM Assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone