MycoBiomDB – Record Details (MyCo_3770)

Biomarker Record Details

Database ID: MyCo_3770
DB IDMyCo_3770
TitleDiagnosis and Outcomes of Fungal Co-Infections in COVID-19 Infections: A Retrospective Study
Year2023
PMID37764170
Fungal Diseases involvedFungal infection
Associated Medical ConditionCOVID-19
GenusCryptococcus
Speciesspp.
OrganismCryptococcus spp.
Ethical StatementThe study was conducted in accordance with the Declaration of Helsinki and approved by the In-stitutional Review Board of Creighton University on 18 October 2021 (IRB #2002584).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortA total of 177 patients were identified as having a positive COVID-19 diagnosis and use of antifungal therapy during their hospitalization. Four patients were identified as having fungal infections prior to hospitalization for COVID and were thus excluded, resulting in 173 patients in the study.
Cohort No.173
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodGM Assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay, GM Assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone