| DB ID | MyCo_3743 |
| Title | Diagnostic value of the serum galactomannan and (1, 3)-β-D-glucan assays for invasive pulmonary aspergillosis in non-neutropenic patients |
| Year | 2014 |
| PMID | 25366000 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | Non-neutropenic Patients |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | This study was approved by the ethics committee of Chinese PLA General Hospital. Informed consent was obtained from all study subjects or their next of kin. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM/BDG |
| Biomarker Full Name | Galactomannan/1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | Between January 2011 and December 2012, 97 patients with suspected IPA admitted to the department of respiratory diseases and the respiratory intensive care unit were prospectively monitored. Serum GM and BG assays were performed before the patients received antifungal therapy. |
| Cohort No. | 97 |
| Age Group | 21-84 |
| P Value | None |
| Sensitivity | 0.704 |
| Specificity | 0.758 |
| Positive Predictive Value | 0.543 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | Glucatell test/FDA Approved -Platelia Aspergillus Ag ELISA |
| ELISA kits | Glucatell test kit (Associates of Cape Cod, Falmouth, USA). |
| Assay Data | None |
| Validation Techniques used | Glucatell test,FDA Approved -Platelia Aspergillus Ag ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
