MycoBiomDB – Record Details (MyCo_3742)

Biomarker Record Details

Database ID: MyCo_3742
DB IDMyCo_3742
TitleDiagnostic value of the serum galactomannan and (1, 3)-β-D-glucan assays for invasive pulmonary aspergillosis in non-neutropenic patients
Year2014
PMID25366000
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNon-neutropenic Patients
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThis study was approved by the ethics committee of Chinese PLA General Hospital. Informed consent was obtained from all study subjects or their next of kin.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortBetween January 2011 and December 2012, 97 patients with suspected IPA admitted to the department of respiratory diseases and the respiratory intensive care unit were prospectively monitored. Serum GM and BG assays were performed before the patients received antifungal therapy.
Cohort No.97
Age Group21-84
P ValueNone
Sensitivity0.481
Specificity0.788
Positive Predictive Value0.481
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodGlucatell test
ELISA kitsGlucatell test kit (Associates of Cape Cod, Falmouth, USA).
Assay DataNone
Validation Techniques usedGlucatell test,FDA Approved -Platelia Aspergillus Ag ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone