MycoBiomDB – Record Details (MyCo_3450)

Biomarker Record Details

Database ID: MyCo_3450
DB IDMyCo_3450
TitleUsing Routine Laboratory Markers and Immunological Indicators for Predicting Pneumocystis jiroveci Pneumonia in Immunocompromised Patients
Year2021
PMID33912176
Fungal Diseases involvedPneumocystis jirovecii pneumonia
Associated Medical ConditionNone
GenusPneumocystis
Speciesjirovecii
OrganismPneumocystis jirovecii
Ethical StatementThis study was approved by the Ethics Committee of Tongji Hospital, Tongji M e d i c a l C o l l e g e , H u a z h o n g U n i v e r s i t y o f S c i e n c e and Technology.
Site of InfectionNone
Opportunistic invasiveOpportunistic
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameCD4
Biomarker Full NameCD4
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationChina
CohortA total of 40 PJP patients (26 males, 14 females; medium age, 52 years; IQR, 23-73 years) were included in the study. Another 40 patients who received immunosuppressive treatment but without signs of infectious diseases, with matched gender, age, and underlying conditions as PJP patients, were enrolled as control group (non-PJP).
Cohort No.40 Patients and 40 control
Age Group44-61
P ValueNone
Sensitivity0.95
Specificity0.8
Positive Predictive Value0.8261
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodFlow Cytometry Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone