| DB ID | MyCo_3407 |
| Title | Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells |
| Year | 2007 |
| PMID | 17442959 |
| Fungal Diseases involved | Cerebral Cryptococcus infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | All studies were approved by the university’s Institutional Animal Care and Use Committee, University of Minnesota, Minneapolis, MN 55455, USA. |
| Site of Infection | Brain |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Brain tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IFNγ |
| Biomarker Full Name | Interferon gamma |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | C57BL/6 mice were obtained from Charles River Laboratories and the National Cancer Institute (Frederick, MD). B6.129S7-Ifngtm1Ts/J (IFN- knockout (KO)), B6.129S7-Ifngr1tm1Agt/J (IFN- R KO), and C57BL/6J wild-type (WT) control mice were purchased from The Jackson Laboratory. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Flow Cytometry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
