| DB ID | MyCo_3400 |
| Title | Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis |
| Year | 2020 |
| PMID | 32596454 |
| Fungal Diseases involved | Cryptococcal meningoencephalitis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | All experiments were approved by the Veterans Affairs Institutional Animal Care and Use Committee under protocol 1408-004 and were performed following NIH guide-lines and the Guide for the Care and Use of Laboratory Animals. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | CXCR3 |
| Biomarker Full Name | CXCR3 |
| Biomarker Type | Negative |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | C57BL/6 mice were obtained from the Jackson laboratory (Bar Harbor, ME). CXCR3−/− mice were bred and housed under specific pathogen–free conditions in the Animal Care Facility at the Veterans Affairs Ann Arbor Healthcare System. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Flow Cytometry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis |
| Up Regulation Down Regulation | Negative |
| Sequence Data | None |
| External Link | None |
