| DB ID | MyCo_3396 |
| Title | Chemokine Receptor 8 Can Distinguish Antineutrophil Cytoplasmic Antibody-Associated Vasculitis From Infectious Complications |
| Year | 2018 |
| PMID | 30899872 |
| Fungal Diseases involved | Cryptococcus infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | spp. |
| Organism | Cryptococcus spp. |
| Ethical Statement | The study protocol was approved by the Ethic Committee of Japan Health Care Organization Sendai Hospital, and written informed consent was obtained from all participants. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CCR8 |
| Biomarker Full Name | Chemokine Receptor-8 |
| Biomarker Type | Negative |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | We performed a cross-sectional study at Japan Health Care Organization Sendai Hospital in Sendai, Japan. A total of 113 patients who were referred to the hospital with vasculitis, including ANCA-associated vasculitis, anti glomerular basement membrane disease, lupus nephritis, and Henoch-Schonlein purpura were enrolled in this study from 2014 to 2016. A total of 25 healthy subjects were enrolled as normal controls. |
| Cohort No. | 113 Patients and 25 control |
| Age Group | 70±15 |
| P Value | p=0.02 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Flow Cytometry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis |
| Up Regulation Down Regulation | Negative |
| Sequence Data | None |
| External Link | None |