| DB ID | MyCo_3390 |
| Title | The CD4+ T-lymphocyte count is an important predictor for the prognosis of cryptococcosis |
| Year | 2016 |
| PMID | 28035481 |
| Fungal Diseases involved | Cryptococcosis |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | spp. |
| Organism | Cryptococcus spp. |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | CD4 |
| Biomarker Full Name | CD4 |
| Biomarker Type | Predictive |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | Between January 2009 and July 2015, a total of 106 proven cases of cryptococcosis were collected for the study. |
| Cohort No. | 106 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Cryptococcosis is a potentially life-threatening systemic my- cosis. Inhalation of Cryptococcus spores is the main route of infection; such spores may remain isolated in the lungs or spread to other organs, depending on the host’s immune status. The central nervous system (CNS) is considered to be the most vulnerable organ involved in this process. Disseminated disease, especially CNS involvement, often points to a need for timely, aggressive treatment and a much higher mor-tality without it [4]. Thus, the risk factors for dissemination (i.e., the host’s immune status or underlying diseases) are al- ways the top concerns of clinicians seeking to manage this infection. |
| Technique | Analytic |
| Analysis Method | Flow cytometry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow cytometry Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
