MycoBiomDB – Record Details (MyCo_3349)

Biomarker Record Details

Database ID: MyCo_3349
DB IDMyCo_3349
TitleLangerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection
Year2018
PMID29782555
Fungal Diseases involvedOropharyngeal candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementAll mouse experiments in this study were conducted in strict accordance with the guidelines of the Swiss Animals Protection Law and were performed under the protocols approved by the Veterinary office of the Canton Zurich, Switzerland (license number 201/2012 and 183/2015). All efforts were made to minimize suffering and ensure the highest ethical and humane standards.
Site of InfectionMouth
Opportunistic invasiveOpportunistic
Sample typeBiopsy
Sample sourceExtracted tongue tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameIL-17
Biomarker Full NameInterleukin-17
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationSwitzerland
CohortNone
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodFlow Cytometry Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis,qRT-PCR, FACS-sorting
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone