| DB ID | MyCo_3320 |
| Title | Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis |
| Year | 2013 |
| PMID | 23663657 |
| Fungal Diseases involved | Fungal sepsis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | Procedures were approved by the Ani- mal Studies Committee at Washington University School of Medicine. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | Anti-CTLA-4 |
| Biomarker Full Name | Anti-cytotoxic T-lymphocyte antigen-4 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Eight-to-ten-week-old male C57BL6 or CD1 mice were purchased from Jackson Laboratory (Bar Harbor, ME, USA) or Charles River Laboratories (Wilmington, MA USA), respectively. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Flow Cytometry Analysis |
| ELISA kits | ELISA Duosets from Invitrogen (Camarillo, CA, USA) and R&D Systems (Minneapolis, MN, USA) |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
