MycoBiomDB – Record Details (MyCo_3304)

Biomarker Record Details

Database ID: MyCo_3304
DB IDMyCo_3304
TitleInterleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia
Year2012
PMID22252873
Fungal Diseases involvedAspergillus fumigatus infection
Associated Medical ConditionPulmonary Eosinophilia
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementAll studies involving mice were approved by the University Committee on Use and Care of Animals at the University of Michigan.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtraxted Lungs tissue
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameIL-17
Biomarker Full NameInterleukin-17
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortWild-type (WT) (C57BL/6J) mice obtained from Jackson Labora- tory (Bar Harbor, ME) were housed under pathogen-free conditions in enclosed filter-topped cages. IL-17 knockout mice were obtained from a breeding colony at the University of Michigan.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodFlow Cytometry Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis, qRT-PCR
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone