| DB ID | MyCo_3301 |
| Title | Toll-like receptor 2 and dectin-1 function as promising biomarker for Aspergillus fumigatus infection |
| Year | 2017 |
| PMID | 29042988 |
| Fungal Diseases involved | Aspergillus fumigatus infection |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The present study was approved by the Ethics Committee of the Second Military Medical University (Nanjing, China). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Cell Line |
| Sample source | Cell Line |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Dectin‑1 |
| Biomarker Full Name | Dendritic cell-associated C-type lectin-1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | Human umbilical vein endothelial cells (HUVECs; cat. no. 3425) were purchased from Nanjing KeyGen Biotech. Co., Ltd. (Nanjing, China). Cells were cultured in the Dulbecco's modified Eagle's medium (DMEM; Invitrogen; Thermo Fisher Scientific, Inc., Waltham, MA, USA) containing 10% fetal bovine serum (Hyclone; GE Healthcare Life Sciences, Logan, UT, USA) supplement with 100 U/ml penicillin and 100 µg/ml streptomycin in a 5% CO2 incubator under 37˚C. The present study was approved by the Ethics Committee of the Second Military Medical University (Nanjing, China). |
| Cohort No. | None |
| Age Group | None |
| P Value | p<0.05 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Analytic |
| Analysis Method | Flow Cytometry Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
