MycoBiomDB – Record Details (MyCo_3300)

Biomarker Record Details

Database ID: MyCo_3300
DB IDMyCo_3300
TitleCXCR4+ granulocytes reflect fungal cystic fibrosis lung disease
Year2015
PMID25929952
Fungal Diseases involvedFungal cystic fibrosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementThis study was conducted in accordance with the amended Declaration of Helsinki. The local independent ethics committees (University of Tübingen, Tübingen, Germany and University of Munich, Munich, Germany) approved the protocol, and written informed consent was obtained from all patients.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameCXCR4+
Biomarker Full NameCXCR4+
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortThe cystic fibrosis group included 19 male and 21 female patients with a mean±SD age of 23±14 years. 10 subjects without pulmonary diseases were selected as the control group.
Cohort No.40 Patients and 10 control
Age Group23±14
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodFlow Cytometry Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedFlow Cytometry Analysis
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone