MycoBiomDB – Record Details (MyCo_3241)

Biomarker Record Details

Database ID: MyCo_3241
DB IDMyCo_3241
TitleClinical evaluation of a (1,3)-beta-D-glucan assay for presumptive diagnosis of Pneumocystis jiroveci pneumonia in immunocompromised patients
Year2009
PMID19692624
Fungal Diseases involvedPneumocystis jirovecii pneumonia
Associated Medical ConditionNone
GenusPneumocystis
Speciesjirovecii
OrganismPneumocystis jirovecii
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortFrom May 2008 to January 2009, 31 serum samples from immunocompromised patients with pneumonia were collected and stored. Thirty-one immunocompromised patients with pneumonia (16 with presumptive pneumocystis pneumonia [PCP] and 15 with non-PCP) were evaluated for serum BG levels.
Cohort No.31
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay, FDA Approved -Platelia Aspergillus Ag ELISA, ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone