MycoBiomDB – Record Details (MyCo_3205)

Biomarker Record Details

Database ID: MyCo_3205
DB IDMyCo_3205
TitleVoriconazole treatment of Candida tropicalis meningitis: persistence of (1,3)-β-D-glucan in the cerebrospinal fluid is a marker of clinical and microbiological failure: A case report
Year2016
PMID27495087
Fungal Diseases involvedCandida tropicalis infection
Associated Medical ConditionNone
GenusCandida
Speciestropicalis
OrganismCandida tropicalis
Ethical StatementNo ethical approval was either sought or obliged in the study.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceCerebrospinal fluid (CSF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortA 49-year-old immune-competent male was admitted to the Neurosurgical Intensive Care for fever (up to 38°C) associated with ideomotor slowdown, severe confusional state, and meningism was included in the study.
Cohort No.1
Age Group49
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone