MycoBiomDB – Record Details (MyCo_3194)

Biomarker Record Details

Database ID: MyCo_3194
DB IDMyCo_3194
TitleInterference of confounding factors on the use of (1,3)-beta-D-glucan in the diagnosis of invasive candidiasis in the intensive care unit
Year2014
PMID25217227
Fungal Diseases involvedInvasive candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementThe study was conducted in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines, and was approved by our ethics committees (Prot. PPC 2395).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortPatients admitted to the ICU department of University of Verona, Italy, between March 2009 and July 2012 were retro- spectively evaluated (n=2,912). A total of 267 patients were tested during the study period.
Cohort No.267
Age Group61.5
P ValueNone
Sensitivity0.829
Specificity0.567
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone