MycoBiomDB – Record Details (MyCo_3193)

Biomarker Record Details

Database ID: MyCo_3193
DB IDMyCo_3193
Title(1-3)-β-D-glucan levels in candidiasis infections in the critically ill neonate
Year2012
PMID22913303
Fungal Diseases involvedInvasive candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementThe study protocol was approved by the Investigational Review Board at Amiens University Medical Center.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
CohortThis retrospective study was performed in the NICU at Amiens University Medical Center (Amiens, France). Data were gathered between December 2010 and March 2012. We included newborns in whom a BDG assay was performed for a suspected ICI and classified as infected (n = 18) or non-infected (n = 43).
Cohort No.18 Patients and 43 control
Age Group25–41 weeks
P Valuep< 0.001
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsNone
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone