| DB ID | MyCo_3145 |
| Title | Effects of host response and antifungal therapy on serum and BAL levels of galactomannan and (1→3)-β-D-glucan in experimental invasive pulmonary aspergillosis |
| Year | 2015 |
| PMID | 26129890 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | The procedures involving an-imals conformed to the Guide for the Care and Use of Laboratory Animals by the Institute for Laboratory Ani-mal Research, Division of Earth and Life Studies, National Research Council, and approval by the Animal Care and Use Committee of the National Cancer Institute. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Rabbit |
| Host Scientific name | Oryctolagus cuniculus |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Female New Zealand White rabbits (Covance Research Products, Inc., Denver, PA) (n= 30) weighing 2.8–3.6 kg were individually housed in facilities accredited by the As- sociation for Assessment and Accreditation of Laboratory Animal Care International. |
| Cohort No. | 30 |
| Age Group | None |
| P Value | p<.05 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | FDA Approved-Fungitell assay |
| ELISA kits | ELISA Kit- PlateliaTM Aspergillus EIA, Bio-Rad Laboratories Red-mond, WA |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | FDA Approved-Fungitell assay, FDA Approved -Platelia Aspergillus Ag ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
