MycoBiomDB – Record Details (MyCo_3139)

Biomarker Record Details

Database ID: MyCo_3139
DB IDMyCo_3139
TitleComparison of lateral flow technology and galactomannan and (1->3)-beta-D-glucan assays for detection of invasive pulmonary aspergillosis
Year2009
PMID19793899
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupAnimal
Host Common namePig
Host Scientific nameCavia porcellus
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortImmunosuppressed male Hartley guinea pigs (Charles River Laboratories) were exposed to conidia for 1 h in an aerosol chamber.
Cohort No.None
Age GroupNone
P ValueNone
Sensitivity1
Specificity0.8
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved-Fungitell assay
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France)
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved-Fungitell assay, FDA Approved -Platelia Aspergillus Ag ELISA, Lateral Flow device analysis
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone