MycoBiomDB – Record Details (MyCo_2938)

Biomarker Record Details

Database ID: MyCo_2938
DB IDMyCo_2938
TitleProspective Evaluation of a New Aspergillus IgG Enzyme Immunoassay Kit for Diagnosis of Chronic and Allergic Pulmonary Aspergillosis
Year2016
PMID26888904
Fungal Diseases involvedChronic and allergic pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameAnti-Aspergillus IgG
Biomarker Full NameAnti-Aspergillus IgG
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
CohortThis prospective study was conducted in the five French university hospitals of Grenoble, Rennes, Lyon, Dijon, and Besançon. Immunocompetent patients with suspected noninvasive aspergillosis were included between January 2013 and April 2015. Here included 352 patients in total. They had a median age of 58.9 years (quartile 1, 47.0 years; quartile 3, 71.5 years), 5% were minors (age, 18 years), and 55% were male.
Cohort No.352
Age Group58.9
P ValueNone
Sensitivity0.917
Specificity0.913
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodFDA Approved -Platelia Aspergillus Ag ELISA
ELISA kitsELISA Kit- Platelia Aspergillus; Bio‐Rad laboratories, Marnes‐la- Coquette, France, ELISA Kit A. fumigatus IgG assay (Bordier Affinity Products)
Assay DataA. fumigatus IgG assay (Virion Serion)
Validation Techniques usedFDA Approved -Platelia Aspergillus Ag ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone