| DB ID | MyCo_2753 |
| Title | Blockade Of PD-1 Attenuated Postsepsis Aspergillosis Via The Activation of IFN-γ and The Dampening of IL-10 |
| Year | 2020 |
| PMID | 31306346 |
| Fungal Diseases involved | Aspergillosis |
| Associated Medical Condition | Sepsis |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The sample accession process was approved by the Ethical Institutional Review Board, Faculty of Medicine, Chulalongkorn University, according to the declaration of Helsinki, with written informed consent. Aspergillus fumigatus Afu06/16 was used in all experiments. The animal protocol conducted following the protocol of National Institutes of Health (NIH), USA, was approved by the Institute Animal Care and Use Committee (IACUC) of Faculty of Medicine, Chulalongkorn University, Bang- kok, Thailand (protocol number 031/2561). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IFN-γ |
| Biomarker Full Name | Interferon gamma |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Thailand |
| Cohort | Eight- to 10-week-old C57/BL6 female mice were purchased from the National Laboratory Animal Center of Mahidol University, Bangkok, Thailand and Nomura Siam International, Bangkok, Thailand. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA based QuantiChrom Creatinine Assay |
| ELISA kits | ELISA Kit (Biolegend, San Diego, Calif) |
| Assay Data | None |
| Validation Techniques used | ELISA based QuantiChrom Creatinine Assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |