| DB ID | MyCo_2713 |
| Title | A novel enzyme immunoassay for the measurement of plasma (1 → 3)-β-D-glucan levels |
| Year | 2020 |
| PMID | 33007318 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | None |
| Genus | None |
| Species | None |
| Organism | None |
| Ethical Statement | This study was approved by the ethics committee of Tsukuba Medical Laboratory of Education and Research Center (Approval No. 2016-4) and Sekisui Medical Co. Ltd (Approval No. 2016-07, 2017-01, 2018-06). |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Human plasma |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | The incidence of invasive fungal infections continues to increase as a consequence of the growing numbers of immunocompromised patients treated with steroids or immunosuppressants and recipients of bone marrow or organ transplants. The most common causative fungi belong to genus Aspergillus and Candida, and the infection of those fungi occurs in various human organs, such as lung, paranasal sinus, blood, and digestive organ. The infection has high risk of developing dyspnea, multiple organ failure, and septic shock. A delay in the initiation of therapy and inadequate antibiotic treatment are highly associated with deterioration of patient prognosis and mortality. Owing to this, the early recognition and diagnosis of fungal infections is imperative for improving patient outcome. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | None |
| Sequence Data | None |
| External Link | None |
