MycoBiomDB – Record Details (MyCo_2562)

Biomarker Record Details

Database ID: MyCo_2562
DB IDMyCo_2562
TitleTNFR1 mRNA expression level and TNFR1 gene polymorphisms are predictive markers for susceptibility to develop invasive pulmonary aspergillosis
Year2010
PMID20646338
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThe study was approved by the ethical review committee of our institution Virgen de las Nieves University Hospital, Granada (Spain).
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypePredictive
BiomoleculeProtein
Geographical LocationSpain
CohortThe present study was conducted at Virgen dealas Nieves University Hospital, Granada (Spain). All participants enrolled were Caucasian and resident in the Granada urban area. All subjects (patients and healthy controls) gave their written informed consent to participate in the study, which was approved by the ethical review committee of our institution. The population consisted of 275 participants (144 immunocompromised haematological patients and 131 healthy controls).
Cohort No.275
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedGM-Platelia™ Aspergillus Ag ELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone