MycoBiomDB – Record Details (MyCo_2544)

Biomarker Record Details

Database ID: MyCo_2544
DB IDMyCo_2544
TitlePreparation and Biological Characterization of Limulus Factor G-activating Substance of Aspergillus spp
Year2017
PMID29187714
Fungal Diseases involvedAspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveOpportunistic
Sample typeBody fluid
Sample sourceSerum
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortAll strains of A. fumigates (NBRC 30870 AND 4470), A. niger (NBRC 6342), A. oryzae (NBRC 30103) and Candida albicans (NBRC 1385) were purchased from the NITE Biological Resources Center (Chiba, Japan), maintained on Sabouraud agar (Difco, Detroit, MI, USA) at 250C and transferred once every three months.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismAspergillus is a medically important fungal genus that causes a life-threatening infection known as aspergillosis in immunocompromised patients. β-1,3-Glucan is detected in the plasma of patients with aspergillosis and appears to be useful for the diagnosis of aspergillosis.
TechniqueAnalytic
Analysis MethodELISA Based
ELISA kitsFungitec G test MK ELISA Kit (Nissui Pharmaceutical Co. Tokyo, Japan), Platelia Aspergillus EIA Test Kit (Bio-rad Laboratories Hercules, CA, USA)
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone