| DB ID | MyCo_2544 |
| Title | Preparation and Biological Characterization of Limulus Factor G-activating Substance of Aspergillus spp |
| Year | 2017 |
| PMID | 29187714 |
| Fungal Diseases involved | Aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | All strains of A. fumigates (NBRC 30870 AND 4470), A. niger (NBRC 6342), A. oryzae (NBRC 30103) and Candida albicans (NBRC 1385) were purchased from the NITE Biological Resources Center (Chiba, Japan), maintained on Sabouraud agar (Difco, Detroit, MI, USA) at 250C and transferred once every three months. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Aspergillus is a medically important fungal genus that causes a life-threatening infection known as aspergillosis in immunocompromised patients. β-1,3-Glucan is detected in the plasma of patients with aspergillosis and appears to be useful for the diagnosis of aspergillosis. |
| Technique | Analytic |
| Analysis Method | ELISA Based |
| ELISA kits | Fungitec G test MK ELISA Kit (Nissui Pharmaceutical Co. Tokyo, Japan), Platelia Aspergillus EIA Test Kit (Bio-rad Laboratories Hercules, CA, USA) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |