| DB ID | MyCo_2498 |
| Title | Epidemiological characteristics of patients with invasive pulmonary aspergillosis infected with Aspergillus fumigatus from a tertiary hospital in Ningxia, China |
| Year | 2025 |
| PMID | 40234690 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | Due to the retrospective nature of this study, informed consent was waived by the Medical Science Ethics Committee of General Hospital of Ningxia Medical University. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM |
| Biomarker Full Name | Galactomannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | A retrospective analysis was conducted on the medical records of 249 inpatients diagnosed with “Aspergillus fumigatus colonization or infection” at Ningxia Medical University General Hospital from January 2018 to December 2023. |
| Cohort No. | 249 |
| Age Group | 21-91 |
| P Value | p<0.001 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive pulmonary aspergillosis (IPA) is a severe fungal infection primarily affecting immunocompromised individuals, such as those with hematologic malignancies, organ transplant recipients, and patients undergoing prolonged corticosteroid therapy. The disease is caused by Aspergillus species, with Aspergillus fumigatus being the most common pathogen. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA Kit- Platelia Aspergillus (Platelia™ Aspergillus Ag, Bio-Rad Laboratories, Hercules, CA, USA) |
| Assay Data | None |
| Validation Techniques used | FDA Approved -Platelia Aspergillus ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
