MycoBiomDB – Record Details (MyCo_2491)

Biomarker Record Details

Database ID: MyCo_2491
DB IDMyCo_2491
TitleA pilot study on nasal wash galactomannan as a surrogate marker for invasive aspergillosis among hematology patients in Thailand
Year2024
PMID39592659
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThe study, conducted in accordance with the amended Declaration of Helsinki, received approval from the Ethics Committee of Ramathibodi Hospital, Bangkok, Thailand (approval no. MURA 2021/125). The committee approved the use of patient samples and data for this study’s publication. Written consent was obtained from all participants.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceNasal wash fluid
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationThailand
CohortThe study included 34 patients, of which 20 were female (58.8%). The median age of the participants was 50.5 years (IQR 36.5–58).
Cohort No.34
Age Group36.5–58
P ValueNone
Sensitivity0.4
Specificity0.8
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia™ Aspergillus Ag, Bio-Rad Laboratories, Hercules, CA, USA)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone