| DB ID | MyCo_2485 |
| Title | Serum galactomannan antigen as a prognostic and diagnostic marker for invasive aspergillosis in heterogeneous medicine ICU patient population |
| Year | 2018 |
| PMID | 29684057 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | Heterogeneous medicine ICU patient |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | This study was approved by the ethics committee of the institute i.e. All India Institute of Medical Sciences, New Delhi, India (Ref no. IESC/T-357/28.09.2012). |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM |
| Biomarker Full Name | Galactomannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | India |
| Cohort | A cohort of 235 patients were included in the study. |
| Cohort No. | 235 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Invasive Aspergillosis (IA) is considered a major threat for hemato-oncological and transplant patients whereas often underestimated in intensive care units (ICUs). Existing literature suggests that the population at risk for IA has expanded to chronic obstructive pulmonary dis- ease (COPD) patients, to the non-transplant intensive care patients; basically it now leans towards patients who do not present with the classical risk factors of IA. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France) |
| Assay Data | None |
| Validation Techniques used | FDA Approved -Platelia Aspergillus ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
