MycoBiomDB – Record Details (MyCo_2481)

Biomarker Record Details

Database ID: MyCo_2481
DB IDMyCo_2481
TitleInvasive aspergillosis in patients with underlying liver cirrhosis: a prospective cohort study
Year2017
PMID28431001
Fungal Diseases involvedInvasive aspergillosis
Associated Medical Conditionliver cirrhosis
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationAustria
Cohort50 patients were included in the study.
Cohort No.150
Age GroupNone
P ValueNone
Sensitivity0.5
Specificity0.97
Positive Predictive Value0.17
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismInvasive aspergillosis (IA) is a disease primarily affecting im-munocompromised patients. Several factors, for example, prolonged neutropenia as well as glucocorticoid use in case of graft-versus-host disease predispose patients for IA. Re- cently, IA has also increasingly been reported in critically ill patients without hematological malignancies and solid organ transplant recipients.
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Vienna, Austria)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone