MycoBiomDB – Record Details (MyCo_2476)

Biomarker Record Details

Database ID: MyCo_2476
DB IDMyCo_2476
TitleCorrelation between Circulating Fungal Biomarkers and Clinical Outcome in Invasive Aspergillosis
Year2015
PMID26107507
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThis prospective study was approved by the Institutional Review Board (IRB) or Ethics Com- mittee of each institution: the IRB of the University of Michigan Medical School; the University of Chicago Division of Biological Sciences and University of Chicago Medical Center IRB; the IRB at Roswell Park Cancer Institute; Stanford IRB; Wayne State University IRB; Fred Hutch- inson Cancer Research Center IRB; the University of Texas M.D. Anderson Cancer Center IRB; Wake Forest University Health Sciences IRB; Summa Health System IRB; the University of Alabama at Birmingham Review Board for Human Use; the University of Minnesota IRB; the University of Arkansas for Medical Sciences IRB; the University of Wisconsin Health Sci- ences IRB; Johns Hopkins Medicine IRB; the University of Pennsylvania IRB; Henry Ford Health System IRB; Oregon Health & Science University IRB; and Universitair Ziekenhuis Leu- ven Medical Ethics Committee.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortFifty-one (44%) of 116 patients enrolled were eligible for evaluation by D14, based on a diagno-sis of proven or probable IA.
Cohort No.51
Age Group19–74
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad Laboratories, Hercules, CA)
Assay DataFDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA
Validation Techniques usedFDA Approved -Platelia Aspergillus ELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone