| DB ID | MyCo_2476 |
| Title | Correlation between Circulating Fungal Biomarkers and Clinical Outcome in Invasive Aspergillosis |
| Year | 2015 |
| PMID | 26107507 |
| Fungal Diseases involved | Invasive aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | This prospective study was approved by the Institutional Review Board (IRB) or Ethics Com- mittee of each institution: the IRB of the University of Michigan Medical School; the University of Chicago Division of Biological Sciences and University of Chicago Medical Center IRB; the IRB at Roswell Park Cancer Institute; Stanford IRB; Wayne State University IRB; Fred Hutch- inson Cancer Research Center IRB; the University of Texas M.D. Anderson Cancer Center IRB; Wake Forest University Health Sciences IRB; Summa Health System IRB; the University of Alabama at Birmingham Review Board for Human Use; the University of Minnesota IRB; the University of Arkansas for Medical Sciences IRB; the University of Wisconsin Health Sci- ences IRB; Johns Hopkins Medicine IRB; the University of Pennsylvania IRB; Henry Ford Health System IRB; Oregon Health & Science University IRB; and Universitair Ziekenhuis Leu- ven Medical Ethics Committee. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GM |
| Biomarker Full Name | Galactomannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Fifty-one (44%) of 116 patients enrolled were eligible for evaluation by D14, based on a diagno-sis of proven or probable IA. |
| Cohort No. | 51 |
| Age Group | 19–74 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad Laboratories, Hercules, CA) |
| Assay Data | FDA- Fungitell®, Cape Cod International, Inc.; Falmounth, MA, USA |
| Validation Techniques used | FDA Approved -Platelia Aspergillus ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |