MycoBiomDB – Record Details (MyCo_2472)

Biomarker Record Details

Database ID: MyCo_2472
DB IDMyCo_2472
TitleGalactomannan testing in bronchoalveolar lavage fluid facilitates the diagnosis of invasive pulmonary aspergillosis in patients with hematologic malignancies and stem cell transplant recipients
Year2010
PMID21087680
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionPatients with Hematologic Malignancies and Stem Cell Transplant Recipients
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementPatients with acute leukemia receiving chemother- apy or undergoing HSCT were eligible for this study, which was approved by, and performed according to the guidelines of the institutional review board at the University of Florida.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameGM
Biomarker Full NameGalactomannan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationUSA
CohortA total of 107 BAL samples from 67 unique pa- tients were submitted for determination of GM index.
Cohort No.67
Age GroupNone
P ValueNone
Sensitivity0.73
Specificity0.89
Positive Predictive Value0.73
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA, Platelia Aspergillus; Bio-Rad, Edmonds, WA)
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus ELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone