MycoBiomDB – Record Details (MyCo_2430)

Biomarker Record Details

Database ID: MyCo_2430
DB IDMyCo_2430
TitleAntibodies against glucan, chitin, and Saccharomyces cerevisiae mannan as new biomarkers of Candida albicans infection that complement tests based on C. albicans mannan
Year2008
PMID18971303
Fungal Diseases involvedCandida albicans infection
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementWritten, informed consent was obtained from all patients before serum sam-ples were taken from the patients, and the study was approved by the institu-tional review board of Lille University Hospital.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameALCA
Biomarker Full Nameantibodies against synthetic disaccharide fragments of glucans (laminaribioside)
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationFrance
CohortSixty-nine serum samples were selected retrospectively between January 2005 and December 2006 from 18 patients hospitalized in Lille University Hospital and Saint Antoine University Hospital, Paris, France, who developed ICIs.
Cohort No.18
Age Group48±19
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedFDA Approved -Platelia Aspergillus Ag ELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone