| DB ID | MyCo_2361 |
| Title | Effects of intranasally dosed posaconazole on fungal load and biomarkers in Aspergillus fumigatus infected immunocompromised mice |
| Year | 2017 |
| PMID | 28699245 |
| Fungal Diseases involved | Aspergillus fumigatus infection |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | All animal studies were approved by the Ethics Review Committee for animal Experimentation of Nihon University. All Aspergillus fu- migatus studies were approved by the Microbial safety Management Committee of Nihon University School of Pharmacy (E- |
| Site of Infection | Lungs |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IL- |
| Biomarker Full Name | Interleukin-17 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | Specific pathogen- |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | Quantikine® mouse ELISA kit (R&D systems, Inc., Minneapolis, MN, USA), OxiSelect® TBARS Assay Kit (Cell Biolabs Inc, San Diego, CA, USA), Platelia Aspergillus- EIA kits (Bio- Rad Laboratories, Redmond, WA, USA). |
| Assay Data | None |
| Validation Techniques used | GM-Platelia™ Aspergillus Ag ELISA, ELISA Based |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
