| DB ID | MyCo_2256 |
| Title | Early transcriptional response of human monocyte-like THP-1 cells in response to Trichosporon asahii infection |
| Year | 2014 |
| PMID | 25179349 |
| Fungal Diseases involved | Invasive Trichosporonosis |
| Associated Medical Condition | None |
| Genus | Trichosporon |
| Species | asahii |
| Organism | Trichosporon asahii |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Invasive/Opportunistic |
| Sample type | Cell Line |
| Sample source | THP-1 Cell line |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | GRK5 |
| Biomarker Full Name | G-protein-coupled receptor kinase 5 |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | China |
| Cohort | The human monocytic THP-1 cell line was obtained from the Cell Resource Center, Chinese Academy of Medical Sciences (PUMC) in Beijing, China. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | 2.85 fold |
| Pathway | None |
| Disease Introduction Mechanism | Invasive trichosporonosis (IT) is an uncommon but frequntly fatal mycosis in immunocompromised patients with a high mortality rate (60–70 %). Trichosporon asahii (T. asahii) was demonstrated to be the major species of invasive Trichosporon infection. In 2003, we identified the first case of disseminated trichosporonosis in China caused by T. asahii. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA, qRT-PCR |
| Up Regulation Down Regulation | Up regulated |
| Sequence Data | None |
| External Link | None |
