| DB ID | MyCo_2164 |
| Title | Lung surfactant protein D (SP-D) response and regulation during acute and chronic lung injury |
| Year | 2013 |
| PMID | 23435873 |
| Fungal Diseases involved | Pneumocystis carinii pneumonia |
| Associated Medical Condition | Chronic Lung Injury |
| Genus | Pneumocystis |
| Species | carinii |
| Organism | Pneumocystis carinii |
| Ethical Statement | The Institutional Animal Care and Use Committees of the University of Pennsylvania and the Danish National Council for Animal Testing have approved the procedures for the use of mice. Thus, the authors declare that the experiments comply with the current laws of the country in which they were performed. |
| Site of Infection | Lungs |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | SP-D |
| Biomarker Full Name | Surfactant protein D |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Female virgin Balb/C mice (Taconic, Denmark), C57/BL6 mice (Charles River Laboratories, Wilmington, MA, USA), and Swiss Black wild-type mice (Taconic, Inc., Germantown, NY, USA) were housed at local animal facilities under controlled conditions, and the national animal welfare committees approved the studies ahead of performance. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA,Immunohistochemistry |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |