MycoBiomDB – Record Details (MyCo_2156)

Biomarker Record Details

Database ID: MyCo_2156
DB IDMyCo_2156
TitleElevation of serum KL-6 levels in patients with hematological malignancies associated with cytomegalovirus or Pneumocystis carinii pneumonia
Year2002
PMID12186700
Fungal Diseases involvedPneumocystis carinii pneumonia
Associated Medical ConditionHematological Malignancies
GenusPneumocystis
Speciescarinii
OrganismPneumocystis carinii
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameKL-6
Biomarker Full NameKL-6
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortThe clinical samples for this study consisted of three patients with non-Hodgkin’s lymphoma and two with adult T-cell leukemia, all of whom were associated with interstitial pneumonitis by P. carinii or CMV. The samples of the patients without complication of interstitial pneumonitis (Non-IP patients) were obtained from five patients with various hemato- logical malignancies or AIDS.
Cohort No.5 Patients and 5 control
Age Group47-81
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone