| DB ID | MyCo_2148 |
| Title | Interleukin-8 and granulocyte colony-stimulating factor in bronchoalveolar lavage fluid and plasma of human immunodeficiency virus-infected patients with Pneumocystis carinii pneumonia, bacterial pneumonia, or tuberculosis |
| Year | 1993 |
| PMID | 7690822 |
| Fungal Diseases involved | Pneumocystis carinii pneumonia |
| Associated Medical Condition | HIV-AIDS |
| Genus | Pneumocystis |
| Species | carinii |
| Organism | Pneumocystis carinii |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-8 |
| Biomarker Full Name | Interleukin-8 |
| Biomarker Type | Prognostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | Here, measured the plasma and bronchoalveolar lavage (BAL) fluid concentrations of the neutrophil-activating cytokmes IL-8 and granulocyte colony-stimulating factor (G-CSF) in 34 HIV-infected patients with PCP (group I, n = 12), bacterial pneumonia (group II, n = 17), or pulmonary tuberculosis (group III, n = 5). Six HIV-seronegative patients (group IV) with non-infectious pulmonary conditions (sarcoidosis, 2; drug-induced lupus, 1; chronic obstructive lung disease, 2; non-small cell lung cancer, 1) served as controls. All patients underwent fiberoptic bronchoscopy with subsequent BAL for diagnostic reasons. |
| Cohort No. | 34 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | sandwich ELISA (Quantikine; R&D Systems, Minneapolis) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
