MycoBiomDB – Record Details (MyCo_2068)

Biomarker Record Details

Database ID: MyCo_2068
DB IDMyCo_2068
Titlec-ANCA positivity in a Belgian patient with pulmonary paracoccidioidomycosis
Year1997
PMID9387974
Fungal Diseases involvedPulmonary paracoccidioidomycosis
Associated Medical ConditionDiffuse interstitial lung disease
GenusParacoccidioides
Speciesbrasiliensis
OrganismParacoccidioides brasiliensis
Ethical StatementNone
Site of InfectionLungs
Opportunistic invasiveOpportunistic
Sample typeBiopsy
Sample sourceTransbronchial biopsies
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker Namec-ANCAs
Biomarker Full NameAntineutrophil Cytoplasmic Antibodies
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationBelgium
CohortA 69 yr old, white male, who underwent coronary artery bypass surgery in 1983, presented with a history of progressive dyspnoea on exertion, chest tightness and a nonproductive cough of 4 month duration. Previous treatment with erythromycin had not improved symptoms. He had a smoking history of 45 pack-years. From 1948 to 1963, the patient worked on a plantation in Paraguay and travelled in Brasil and Argentina.
Cohort No.1
Age Group69
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsELISA (immunoglobulin G (IgG)) kit (Euroimmun, Groß Grönau, Germany)
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone