| DB ID | MyCo_2063 |
| Title | Gross, histological and immunohistochemical features of mucormycosis in the platypus |
| Year | 2000 |
| PMID | 10906254 |
| Fungal Diseases involved | Mucormycosis |
| Associated Medical Condition | None |
| Genus | Mucor |
| Species | amphibiorum |
| Organism | Mucor amphibiorum |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Biopsy |
| Sample source | Biopsies from skin lesions |
| Host Group | Animal |
| Host Common name | Platypus |
| Host Scientific name | Ornithorhynchus anatinus |
| Biomarker Name | CD4 |
| Biomarker Full Name | CD4 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Australia |
| Cohort | Biopsies were obtained from seven of 14 adult free living platypuses (nos 1–14) with mucormycosis captured from streams in northern Tasmania by the methods of Grant and Carrick (1974). Platypus 3 was captured three times within 97 days and two biopsies were taken. Platypus 8, which had been captured three times, was found dead and scavenged 24 days after initial capture, and platypus 4 was found dead 72 days after capture; both were in an emaciated and autolytic state. |
| Cohort No. | 14 |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Mucorales is the largest order of the Zygomycetes class of fungi and includes several important potential pathogens such as species of Mucor, Rhizopus, Rhizomucor, Absidia, Mortierella, Cunninghamella, Syncephalastrum and Saksenaea. Members of the Mucorales are found in decaying vegetation, animal dung and soil. Their pathogenicity is usually no more than mild, except under conditions such as immuno-suppression or concurrent disease. The largest genus of the Mucorales is Mucor, with 60 species. Mucormycosis in amphibians is associated with multiple white nodules in many organs. Mucor amphibiorum in infected tissues occurs as sphaerules containing daughter sphaerules, but in culture the hyphal form is more usual. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | None |
| Sequence Data | None |
| External Link | None |
