| DB ID | MyCo_2047 |
| Title | A case series of histoplasmosis patients with elevated serum soluble interleukin-2 receptor levels |
| Year | 2017 |
| PMID | 28395939 |
| Fungal Diseases involved | Histoplasmosis |
| Associated Medical Condition | None |
| Genus | Histoplasma |
| Species | capsulatum |
| Organism | Histoplasma capsulatum |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | sIL-2R |
| Biomarker Full Name | soluble interleukin-2 receptor |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | Here report a case series of histoplasmosis in three Japanese temporary workers in Manzanillo, Mexico. All three patients developed a persistent high fever and general fatigue. |
| Cohort No. | 3 |
| Age Group | 32-65 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Histoplasmosis is caused by inhalation of Histoplasma capsu-latum. Although endemic areas of histoplasmosis are North and Central America, it is occasionally seen worldwide, including South America, Africa, Eastern Asia, Eastern and Southern Europe, and Australia. In Japan, histoplasmosis is usually considered as im- ported mycosis because most patients have a travel history to endemic areas and few patients are infected within Japan. The number of histoplasmosis patients has been increasing in recent years in proportion to the increasing number of Japanese overseas travelers, with a total of 83 cases reported up to August 2015. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
