| DB ID | MyCo_2043 |
| Title | Regulation of infection with Histoplasma capsulatum by TNFR1 and -2 |
| Year | 2000 |
| PMID | 10946295 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | None |
| Genus | Histoplasma |
| Species | capsulatum |
| Organism | Histoplasma capsulatum |
| Ethical Statement | All animal experiments were done in accordance with the Animal Welfare Act guidelines of the National Institutes of Health. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Homogenized tissue extracts |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IFNγ |
| Biomarker Full Name | Interferon gamma |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | TNFR1 / , TNFR2 / , and C57BL/6 mice (5 wk of age) were purchased from The Jackson Laboratory (Bar Harbor, ME). |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA kits (Endogen, Cambridge, MA), Elisa Kit IL-10 (R&D Sys-R&D Sys-tems, Minneapolis, MN) , IL-12 sandwich ELISA kit (PharMin-gen) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
