| DB ID | MyCo_2015 |
| Title | Circulating soluble CD4 directly prevents host resistance and delayed-type hypersensitivity response to Cryptococcus neoformans in mice |
| Year | 2000 |
| PMID | 11220677 |
| Fungal Diseases involved | Fungal infection |
| Associated Medical Condition | None |
| Genus | Cryptococcus |
| Species | neoformans |
| Organism | Cryptococcus neoformans |
| Ethical Statement | The experimental protocols were approved by the Ethics Review Committee for Animal Experimentation of the university, University of the Ryulgus, Okinawa 903-0215, Japan. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IL-4 |
| Biomarker Full Name | Interleukin-4 |
| Biomarker Type | Negative |
| Biomolecule | Protein |
| Geographical Location | Japan |
| Cohort | Female mice with a mutant cd4 gene result- ing in the defective expression of membrane-bound CD4 (mCD4D mice) were used in the present experiments at the age of 7-12 weeks. |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA kits (Endogen, Inc. for IFN-y and IL-4; Genzyme, Cam- bridge, Mass., U.S.A. for IL-12p40; R&D Systems, Minneapolis, Minn., U.S.A. for IL-13; and Medical Biology Laboratory, Co., Nagoya, Japan, for IL-18). |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Negative |
| Sequence Data | None |
| External Link | None |
