| DB ID | MyCo_1977 |
| Title | Aquaporin 5-in Extracellular Vesicles of Human Vitreous as a Potential Marker for Fungal Endophthalmitis |
| Year | 2023 |
| PMID | 37027237 |
| Fungal Diseases involved | Fungal endophthalmitis |
| Associated Medical Condition | None |
| Genus | Colletotrichum |
| Species | spp. |
| Organism | Colletotrichum spp. |
| Ethical Statement | The study was sanctioned by the Institutional Ethics Board (Ref No. LEC 12–19-371) and all the procedures involved were performed in accordance with the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Vitreous fluid |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | AQP5 |
| Biomarker Full Name | Aquaporin 5 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | India |
| Cohort | Here, Vitreous fluid was collected from 20 patients clinically suspected as FE, 10 patients from non-infectious conditions, and 10 patients with bacterial endophthalmitis as controls. |
| Cohort No. | 20 Patients and 20 control |
| Age Group | Feb-76 |
| P Value | None |
| Sensitivity | 1 |
| Specificity | 0.9 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | Human Aquaporin-5 ELISA Kit (MBS763015, myBioSource) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |