| DB ID | MyCo_1886 |
| Title | Detection of the Candida antigen mannan in cerebrospinal fluid specimens from patients suspected of having Candida meningitis |
| Year | 2004 |
| PMID | 14766875 |
| Fungal Diseases involved | Candida meningitis |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Cerebrospinal fluid (CSF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Mn |
| Biomarker Full Name | Mannan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | The Netherlands |
| Cohort | Here, report on five patients who were treated for CNS candidosis and for whom we evaluated the diagnostic value of mannan antigen detection in CSF. A 4-year-old girl was admitted to our hospital be-cause of a relapse of acute nonlymphatic leukemia for which she had been treated with chemotherapy in the previous 6 months. A 60-year-old male was admitted to our hospital because of an organic psychosyndrome. No signs of meningism were present. A 48-year-old male with dermatomyositis and treated with prednisone and immuran, was readmitted to the hospital with fever, dysarthria, persistent uveitis, and head- ache. A dysmature and premature female neonate (birth weight, 700 g; born at 26 weeks of gestation) was admitted to the neonatal intensive care unit. A 76-year-old female was admitted because of a relapse of a retroauricular basal cell carcinoma. |
| Cohort No. | 5 |
| Age Group | 0-76 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
