| DB ID | MyCo_1820 |
| Title | Increased Urine Interleukin-17 and Interleukin-22 Levels in Patients With Candidal Urinary Tract Infection |
| Year | 2018 |
| PMID | 29421775 |
| Fungal Diseases involved | Candiduria |
| Associated Medical Condition | Urinary Tract Infection |
| Genus | Candida |
| Species | glabrata |
| Organism | Candida glabrata |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Urine |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | IL-17 |
| Biomarker Full Name | Interleukin-17 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Iran |
| Cohort | A case-control study was conducted on inpatients at Hashemi Nejad Kidney Center. Thirty-four patients were identified with Candida species in their urine samples (> 103 colony-forming units per milliliter and presence of Candida species only). |
| Cohort No. | 34 |
| Age Group | 17-89 |
| P Value | p=.04 |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Candiduria, the presence of Candida species in urine specimen, is a common finding in hospitalized patients. Candida albicans is the most frequent causative organism of candiduria. The host risk factors to develop candiduria include urinary catheter or urinary tract abnormality, older age, female sex, prior antibiotic use, hospitalization in intensive care units and diabetes mellitus. The majority of candiduric patients reveal no symptoms, while few numbers of them present symptoms such as fever, dysuria, and flank pain. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | eBioscence enzyme-linked immunosorbent assay kit (USA) |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
