MycoBiomDB – Record Details (MyCo_1813)

Biomarker Record Details

Database ID: MyCo_1813
DB IDMyCo_1813
TitleIL-10 is required for development of protective Th1 responses in IL-12-deficient mice upon Candida albicans infection
Year1998
PMID9834110
Fungal Diseases involvedCandida albicans infection
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementProcedures involving animals and their care were conducted in conformity with national and international laws and policies.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceExtracted cell supernatant
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameIL-12
Biomarker Full NameInterleukin-12
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortBreeding pairs of homozygous IL-12 p40-deficient (IL-12 p40 / ) and control IL-12 p40 / BALB/c mice (28) kindly provided by Dr. J. Magram (Hoffmann-La Roche, Nutley, NJ) were bred under specific pathogen-free conditions. Mice of both sexes, 8–10 wk old, were used.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone