| DB ID | MyCo_1799 |
| Title | Primary role for CD4(+) T lymphocytes in recovery from oropharyngeal candidiasis |
| Year | 2002 |
| PMID | 11796605 |
| Fungal Diseases involved | Oropharyngeal candidiasis |
| Associated Medical Condition | AIDS |
| Genus | Candida |
| Species | albicans |
| Organism | Candida albicans |
| Ethical Statement | Animal experiments were approved by the Animal Experimentation Ethics Committee of the University of Queensland and were carried out in accordance with the National Health and Medical Research Council’s Australian Code of Practice for the Care and Use of Animals for Scientific Purposes, 1997. |
| Site of Infection | None |
| Opportunistic invasive | Opportunistic |
| Sample type | Body fluid |
| Sample source | Cervical Lymph |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IFN-γ |
| Biomarker Full Name | Interferon gamma |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Australia |
| Cohort | Specific-pathogen-free BALB/c and CBA/CaH female nude mice, their heterozygous littermates, and euthymic controls, 6 to 8 weeks of age, were purchased from the Animal Resources Centre, Perth, or from the Walter and Eliza Hall Institute, Melbourne, Australia. |
| Cohort No. | None |
| Age Group | 6-8 Weeks |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Oral candidiasis is a predominant feature in patients suffering from human immunodeficiency virus (HIV) and AIDS, and these patients, as well as those with chronic mucocutaneous candidiasis, commonly exhibit defects in cell mediated immunity. |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | ELISA, FACS,RT-PCR |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |