MycoBiomDB – Record Details (MyCo_1743)

Biomarker Record Details

Database ID: MyCo_1743
DB IDMyCo_1743
TitleDecreased Cell Wall Galactosaminogalactan in Aspergillus nidulans Mediates Dysregulated Inflammation in the Chronic Granulomatous Disease Host
Year2016
PMID27142572
Fungal Diseases involvedInvasive aspergillosis
Associated Medical ConditionChronic Granulomatous Disease
GenusAspergillus
Speciesnidulans
OrganismAspergillus nidulans
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameTNF-α
Biomarker Full NameTumor Necrosis Factor alpha
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationThe Netherlands
CohortAfter informed consent was given, venous blood was drawn from healthy volunteers and four CGD patients (two gp91phox deficient and two p47phox deficient). All patients were below the age of 18 and free from any infectious or inflammatory diseases.
Cohort No.4
Age Group<18
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsNone
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone