| DB ID | MyCo_1707 |
| Title | Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus |
| Year | 2024 |
| PMID | 39138196 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | Blood samples from healthy human donors were obtained from the Etablissement Français du Sang Trinité (Paris, France) with written informed consent as per Institutional (Institut Pasteur) Ethics Com- mittee guidelines (convention 12/EFS/023). Serum samples used in ou study, which were collected from the groups of controls and infected patients. This study complies with the ethical and legal requirements of the French law (15th April 2019) and the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | PTX3 |
| Biomarker Full Name | Pentraxin 3 |
| Biomarker Type | Diagnostic/Prognostic |
| Biomolecule | Protein |
| Geographical Location | France |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | LEGEND MAXTM Human PTX3 ELISA kit (BioLegend, USA; sensitivity 17.1 pg/mL). |
| Assay Data | None |
| Validation Techniques used | ELISA |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |