MycoBiomDB – Record Details (MyCo_1707)

Biomarker Record Details

Database ID: MyCo_1707
DB IDMyCo_1707
TitleInterplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus
Year2024
PMID39138196
Fungal Diseases involvedInvasive pulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementBlood samples from healthy human donors were obtained from the Etablissement Français du Sang Trinité (Paris, France) with written informed consent as per Institutional (Institut Pasteur) Ethics Com- mittee guidelines (convention 12/EFS/023). Serum samples used in ou study, which were collected from the groups of controls and infected patients. This study complies with the ethical and legal requirements of the French law (15th April 2019) and the Declaration of Helsinki.
Site of InfectionNone
Opportunistic invasiveInvasive
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePTX3
Biomarker Full NamePentraxin 3
Biomarker TypeDiagnostic/Prognostic
BiomoleculeProtein
Geographical LocationFrance
CohortNone
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueELISA
Analysis MethodELISA Based
ELISA kitsLEGEND MAXTM Human PTX3 ELISA kit (BioLegend, USA; sensitivity 17.1 pg/mL).
Assay DataNone
Validation Techniques usedELISA
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone