| DB ID | MyCo_1705 |
| Title | Distinguishing Invasive from Chronic Pulmonary Infections: Host Pentraxin 3 and Fungal Siderophores in Bronchoalveolar Lavage Fluids |
| Year | 2022 |
| PMID | 36422015 |
| Fungal Diseases involved | Invasive pulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | spp. |
| Organism | Aspergillus spp. |
| Ethical Statement | Routine diagnostic BALF sampling in the observational part of the study was approved by the Ethics Committee for Clinical Trials of the Institute of Public Health (EC-02/18) and University Hospital Ostrava (448/2018) and informed consent documents were collected from study participants. |
| Site of Infection | None |
| Opportunistic invasive | Invasive |
| Sample type | Body fluid |
| Sample source | Bronchoalveolar lavage fluid (BALF) |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Ptx3 |
| Biomarker Full Name | Pentraxin 3 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Czech Republic |
| Cohort | 89 patients enrolled into this retrospective study, 22 had some form of PA, while the remaining 67 served as controls. |
| Cohort No. | 22 Patients and 67 control |
| Age Group | None |
| P Value | None |
| Sensitivity | 1 |
| Specificity | 0.98 |
| Positive Predictive Value | 0.95 |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | ELISA |
| Analysis Method | ELISA Based |
| ELISA kits | ELISA kit BioVendor (Czech Republic) |
| Assay Data | None |
| Validation Techniques used | ELISA, LC-MS |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
